GT80 Fully Automatic Potential Titrator with Automatic Sampler for Mass Determination

Overview

The GT80 Fully Automatic Potential Titrator revolutionizes analytical chemistry by integrating precision potentiometric titration with an advanced automatic sampler, delivering unparalleled accuracy for mass determination in diverse applications. Designed for laboratories demanding high-throughput analysis without compromising data reliability, this instrument combines cutting-edge technology with user-friendly operation to streamline workflows.

At its core, the GT80 utilizes a dual-electrode system to monitor potential changes during titration, ensuring real-time detection of equivalence points with micromolar sensitivity. The built-in automatic sampler accommodates up to 100 sample vials, enabling unattended batch analysis and reducing manual intervention. Whether used in pharmaceuticals, environmental testing, or chemical manufacturing, the GT80 sets a new standard for efficiency and precision, making it an indispensable tool for quantitative chemical analysis.

Features

1. Precision Potentiometric Titration

Equipped with a high-resolution electrode module, the GT80 measures potential differences with ±0.1 mV accuracy, ensuring precise endpoint detection for both acid-base and redox titrations. The adaptive titration algorithm dynamically adjusts drop size—from 0.001 mL micro-drops near endpoints to 0.1 mL rapid additions in pre-titration phases—optimizing both speed and accuracy.

2. Automatic Sampler Integration

The robotic sampler features a 3-axis motion system with sub-millimeter positioning precision, capable of handling samples ranging from 1 mL micro-vials to 100 mL beakers. Barcode scanning functionality eliminates sample mix-ups, while the intuitive software allows customizable sampling sequences, including dilution protocols and blank subtraction routines.

3. Compliance & Data Integrity

Built to meet ISO 17025 and 21 CFR Part 11 standards, the GT80 includes secure user authentication, audit trails, and encrypted data storage. The integrated thermal printer generates GLP-compliant reports with timestamped results, while USB/Ethernet connectivity enables seamless data transfer to LIMS systems.

4. Robust Mechanical Design

The titrator’s chemically resistant PTFE fluid path and stainless-steel pump ensure compatibility with aggressive reagents, including concentrated acids and bases. A built-in leak detection system triggers automatic shutdown, protecting the instrument from damage and ensuring operator safety.

Applications

Pharmaceutical Quality Control

In pharmaceutical labs, the GT80 excels in active ingredient quantification, such as determining the purity of APIs through acid-base titration. Its automatic sampler efficiently processes multiple batches of tablets or injectables, ensuring compliance with pharmacopoeia standards (USP, EP, JP) by delivering RSD values <0.1% for repetitive measurements.

Environmental Analysis

For water and soil testing, the instrument accurately measures parameters like total hardness, chloride ion concentration, and chemical oxygen demand (COD) via redox titration. The automatic sampler handles up to 50 environmental samples overnight, reducing turnaround time for regulatory compliance reports.

Chemical Research & Development

R&D teams use the GT80 to characterize new compounds through complex titration curves, such as determining pKa values of organic acids. The instrument’s real-time data visualization software allows instant analysis of titration graphs, facilitating rapid method development for novel formulations.

Food & Beverage Industry

In quality assurance labs, the GT80 measures acidity in wines, alkalinity in dairy products, and salt content in processed foods. The automatic dilution feature simplifies analysis of high-concentration samples, ensuring consistent results across diverse matrices.

Operation and Parameter Settings

1. How to set up the batch analysis process of the automatic sampler?

  First, create a sample sequence through the instrument supporting software, associating sample numbers, positions, and corresponding titration methods. Ensure that the sample bottles are placed in order on the 20 station turntable and that the pipelines are firmly connected. After starting, the instrument will automatically complete the entire process of sample loading, titration, cleaning, and record the result curve.

2. How to ensure the accuracy of the mass determination function?

  Regularly calibrate the balance module using standard weights for linear verification. Meanwhile, ensure that the burette resolution (1/48,000) and closed loop control accuracy (0.003mm) meet the experimental requirements. If the result deviation exceeds ±0.1%, it is recommended to check the balance sensor or contact the manufacturer for calibration.

3. How to switch the multi channel liquid addition module?

  Select the target channel through the software interface. The system supports 8 channel expansion. Before switching, rinse the pipeline with distilled water to avoid cross contamination. For corrosive reagents (such as perchloric acid), ensure that the PTFE material pipeline and rotary valve are well sealed.

Typical Applications:

Acid value in food, Determination of chloride ion in cement,

Determination of peroxide values in food, Determination of thiol sulfur,

Measurement of reducing sugars in food, Electrolyte determination.